Many a vet has been filled with dread when confronted with a case of feline chronic gingivostomatitis. The mere thought of performing multiple surgical extractions in a cat, never mind the uncertainty that shrouds treatment recommendations for this condition and the shocked response of clients to those recommendations, is enough to make most vets run for the hills. In this lecture, we will discuss this anxiety inducing disease in a step wise fashion, so that you can make an accurate diagnosis, make treatment recommendations with conviction, and confidently carry out that treatment plan. To achieve this, we will start by reviewing the relevant feline oral anatomy and briefly revising other pathologies associated with oral inflammation. The current understanding of the pathophysiology of feline chronic gingivostomatitis will be discussed, as well as recommended treatment options. Short-, medium- and long-term management of cats suffering with this condition, particularly refractory cases, will be chewed over. To bring it all together, we will work through several case examples so that you can tackle your own cases with confidence and help more of our feline friends live a happy, pain-free life. References available upon request.