resulted in several heritable health conditions. This article reports a five-case series of Burmese cats with supernumerary premolar teeth. All included cases displayed either unilateral or bilateral supernumerary maxillary fourth premolar teeth, which has not been reported previously in the literature. Two cases also displayed supernumerary mandibular fourth premolar teeth, while in another case bilateral supernumerary maxillary third incisor teeth were found. Examination of the pedigrees of the affected cats revealed that all five cats were related with one common ancestor. All patients in this case series were successfully treated. Breeders and owners must be made aware of the condition in order to institute early evaluation, diagnosis and treatment.